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A study in the journal Brain and Cognition in 2000 found that "nicotinic stimulation may have promise for improving both cognitive and motor aspects of Parkinson's disease." Another, in Behavioral Brain Research, suggested "there is considerable potential for therapeutic applications in the near future." Other work has looked at the stimulant's potential for easing symptoms of attention deficit hyperactivity disorder (ADHD)

A spirometry test, as well as some others diagnostic procedures were used to measure their airway resistance

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